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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF3
All Species:
16.97
Human Site:
T221
Identified Species:
33.94
UniProt:
Q9NR23
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR23
NP_065685.1
364
41387
T221
V
N
F
Q
P
E
D
T
C
A
R
L
R
C
S
Chimpanzee
Pan troglodytes
XP_508988
364
41318
T221
V
N
F
Q
P
E
D
T
C
A
R
L
R
C
S
Rhesus Macaque
Macaca mulatta
XP_001112644
364
41302
T221
V
N
F
Q
P
E
D
T
C
A
R
L
R
R
S
Dog
Lupus familis
XP_534896
365
41219
T221
V
N
F
Q
L
Q
D
T
C
A
R
L
R
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q07104
366
41509
P222
V
T
V
Q
P
E
N
P
C
D
P
L
L
R
S
Rat
Rattus norvegicus
P49001
393
44364
L230
F
V
V
E
V
A
H
L
E
E
K
P
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509474
383
41376
A239
D
G
N
G
T
E
A
A
C
A
S
L
G
R
S
Chicken
Gallus gallus
Q90751
353
40328
S213
S
L
H
Q
D
E
D
S
W
S
Q
L
R
P
L
Frog
Xenopus laevis
Q9YGV1
354
40298
V211
G
G
N
R
S
F
V
V
C
E
P
I
Q
S
F
Zebra Danio
Brachydanio rerio
P35621
355
40183
H212
L
N
N
M
L
H
D
H
A
Y
V
Q
I
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
S291
R
S
F
T
H
K
D
S
K
I
D
D
R
F
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
E241
R
G
S
Q
V
I
K
E
L
G
A
I
S
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.4
80.2
N.A.
69.4
29.2
N.A.
43.5
30.2
42.3
42
N.A.
22.1
N.A.
N.A.
30.6
Protein Similarity:
100
99.4
98
87.4
N.A.
79.7
47
N.A.
58.7
49.7
59.6
60.7
N.A.
37.9
N.A.
N.A.
48.3
P-Site Identity:
100
100
93.3
80
N.A.
46.6
6.6
N.A.
33.3
33.3
6.6
13.3
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
53.3
20
N.A.
33.3
53.3
26.6
20
N.A.
40
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
9
9
42
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
59
0
0
0
0
17
0
% C
% Asp:
9
0
0
0
9
0
59
0
0
9
9
9
0
0
9
% D
% Glu:
0
0
0
9
0
50
0
9
9
17
0
0
0
0
0
% E
% Phe:
9
0
42
0
0
9
0
0
0
0
0
0
0
9
9
% F
% Gly:
9
25
0
9
0
0
0
0
0
9
0
0
17
0
0
% G
% His:
0
0
9
0
9
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
17
9
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
9
0
9
0
0
9
9
% K
% Leu:
9
9
0
0
17
0
0
9
9
0
0
59
9
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
25
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
34
0
0
9
0
0
17
9
0
17
9
% P
% Gln:
0
0
0
59
0
9
0
0
0
0
9
9
9
9
0
% Q
% Arg:
17
0
0
9
0
0
0
0
0
0
34
0
50
25
0
% R
% Ser:
9
9
9
0
9
0
0
17
0
9
9
0
9
9
59
% S
% Thr:
0
9
0
9
9
0
0
34
0
0
0
0
0
0
0
% T
% Val:
42
9
17
0
17
0
9
9
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _